Poor Outcomes in Patients with Primary Malignant Mediastinal Germ-cell Tumors
نویسندگان
چکیده
منابع مشابه
Management of the primary malignant mediastinal germ cell tumors: experience with 54 patients
BACKGROUND Primary malignant mediastinal germ cell tumor (PMMGCT) is rare and sometimes the prognosis of the patients with PMMGCT is not very satisfactory. METHODS A total of 54 patients with PMMGCT in a follow-up from 1990 to 2009. We evaluated the role of the surgical treatment and the effect of multimodality treatment strategy for patients with PMMGCT. RESULTS Fifty-two patients underwen...
متن کاملHematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors.
BACKGROUND The association between primary germ cell tumors of the mediastinum (the space between the lung pleura that contains the heart and other chest viscera) and hematologic malignancies has been described by retrospective analysis of patients treated at individual clinical centers. To better characterize the risk of hematologic disorders in patients with extragonadal germ cell tumors and ...
متن کاملSecondary malignant melanoma in primary mediastinal germ cell tumour.
Secondary transformation in Germ Cell Tumours (GCT) is an extremely rare event. We report here a case of malignant melanoma arising in primary mediastinal GCT. A young male presented with new onset dyspnoea and a mediastinal mass. As serum alpha fetoprotein was raised, a diagnosis of primary mediastinal GCT was made. He achieved remission with standard chemotherapy and resection of the mass. Af...
متن کاملA Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy
OBJECTIVES Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat. Herein, we examined patients with PMGCTs who underwent multimodal treatment. METHODS We examined 6 patients (median age: 25 years, range: 19-27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015. Three patients had seminomas, 2 patients had yolk sa...
متن کاملRole of post-chemotherapy radiation in the management of children and adolescents with primary advanced malignant mediastinal germ cell tumors
OBJECTIVE Primary malignant mediastinal germ cell tumors (MMGCTs) are rare in children and adolescents and have a poorer prognosis than their gonadal counterparts. We report a single institutional experience of a 10-year period of primary advanced MMGCTs treated with chemotherapy, followed by radiotherapy in those who had residual mass. METHODS Children and adolescents with primary advanced M...
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ژورنال
عنوان ژورنال: The Kaohsiung Journal of Medical Sciences
سال: 2005
ISSN: 1607-551X
DOI: 10.1016/s1607-551x(09)70208-6